| 引用本文: | 梁梦园，范德玲，古文，刘济宁，石利利.环境介质中有机污染物非靶向筛查技术研究进展[J].环境监控与预警,2020,12(5):14-20 |
| LIANG Meng-yuan, FAN De-ling, GU Wen, LIU Ji-ning, SHI Li-li.Research Development of Non targeted Screening Techniques for Pollutants in Enviromental Media[J].Environmental Monitoring and Forewarning,2020,12(5):14-20 |
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| 摘要: |
| 随着质谱质量精度的不断提高和物质数据库的扩大，高通量非靶向筛查技术快速发展，为组成复杂的环境介质中污染物的识别分析提供了有效手段。综述了环境分析中非靶向筛查技术［气相色谱-高分辩率质谱法（GC-HRMS）和液相色谱-高分辨率质谱法（LC-HRMS）］的研究进展，包括样品的前处理方法、非靶向分析平台、数据分析及存在的问题。简述了非靶向筛查技术在分析环境水样、沉积物样品及土壤样品中的应用，并提出该技术存在的问题和应用前景。 |
| 关键词: 环境介质 非靶向筛查 高分辨率质谱 数据库 |
| DOI： |
| 分类号:X830 |
| 文献标识码:A |
| 基金项目:国家重点研发计划基金资助项目（2019YFC1803404） |
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| Research Development of Non targeted Screening Techniques for Pollutants in Enviromental Media |
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LIANG Meng-yuan, FAN De-ling, GU Wen, LIU Ji-ning, SHI Li-li
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Nanjing Institute of Environmental Sciences of Ministry of Ecology and Environment, Nanjing, Jiangsu 210042, China
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| Abstract: |
| With the improvement of mass accuracy in mass spectrometry and the expansion of the material database, the high throughput non targeted screening techniques developrapidly, which provides an effective means for the analysis and identification of pollutants in complex environmental media. This paper summarizes the advances of non targeted screening techniques ［gas chromatography high resolution mass spectrometry (GC HRMS) and liquid chromatography high resolution mass spectrometry (LC HRMS) ］ in environmental sample analytical methods, including sample pretreatment methods, non targeted analysis platforms, data analysis and current challenges. The applications of non targeted screening techniques for analyzing water, sediment and soil samples are reviewed as well, and the existing problems and application prospect are promoted. |
| Key words: Environmental media Non targeted screening techniques High resolution mass spectrometry Database |
