An ionchromatography with UV detection method was established for simultaneous determination of 5 chlorophenols in water samples. The water sample was filtered through a 0.45 μm aqueous phase syringe filter, the detection wavelength was set by 250 nm, and the mobile phase was a mixed solution of 5% ammonia in methanol and 1% ammonium sulfate solution in a volume ratio of 80∶20. The results showed that when the concentration of 2chlorophenol was in the range of 0.1～1.6 mg/L, and the other four chlorophenols in the range of 0.01～0.16 mg/L, the linear correlation coefficients were all greater than 0.999. The detection limits of 2chlorophenol and 2,4dichlorophenol were 0.03 and 0.004 mg/L respectively. The detection limit of the remaining three chlorophenols was 0.003 mg/L. The recovery rates of standard addition at low, medium and high concentration level were in the range of 94.1%～100.8%, with the relevant standard deviations (RSD) ranged from 2.5% to 9.9%. With simple pretreatment, the method showed high sensitivity, good accuracy and precision, is suitable for daily fast determination of five chlorophenol compounds in drinking water samples.